Topical Wound Oxygen Therapy
A safe, non-invasive, adjunctive therapy that helps address the fundamental reasons chronic wounds fail to heal.
A Unique Multi-modal Approach
High pressure delivery results in greater tissue diffusion critical to restoring normal wound metabolism, resulting in more effective and durable healing.
Non-contact cyclical compression addresses edema and helps correct for the underlying peripheral vascular disease.
Assures an ideal moist wound environment, promoting healthy granulation tissues for faster, more effective and durable healing.
The Benefits of TWO2 Therapy
80% Wound Closure Rate
Unprecedented closure rates in all wound stages
Significant Pain Reduction
Rapid reduction in wound related pain by over 75% within 3-4 weeks of commencing treatment.
The ability to reduce healing times and complications can lead to significant cost savings.
Non Invasive Safe Therapy
Topical Wound Oxygen Therapy is easily applied and integrated into any Acute, Long Term and/or Chronic Wounds.
Before & After TWO2 Therapy
TWO2 Therapy System Components
In-home Controller provides time therapy and cyclical pressure. Oxygen Concentrator is provided separately.
Medium and large single-use extremity chamber.
Frequently Asked Questions
Will my patients be able to use the Therapy themselves; I am concerned about ease of use and compliance?
Yes, most patients do not need assistance to use TWO2 therapy. TWO2 therapy has a few simple set up steps. Before first use, the patient will be instructed on how to set up and use the TWO2 therapy. Additionally, easy instructions are provided on the screen of the TWO2 Controller to guide the patient step-by-step.
Each Extremity Chamber session is for 90 minutes, as recommended by the treating clinician. Patients often complete their session while enjoying other activities such as reading, watching television, or the like.
The duration of the Therapy depends on the severity and complexity of the wound.
TWO2 therapy is not painful.
TWO2 therapy can be performed at any time. It is best to perform TWO2 therapy when the Patient can comfortably sit or lay down for the duration of the treatment.
TWO2 therapy can be used on acute and chronic wounds where it is determined to be clinically necessary or beneficial.
Wound Types and Management
TWO2 therapy is cleared for use for treating chronic and acute wounds.
Using TWO2 therapy does not change what you do as part of standard of care for wound bed preparation, which includes debridement of devitalized and necrotic tissue, moisture and infection management.
TWO2 should not be used in the presence of acute thrombophlebitis, or Deep Vein Thrombosis.
Yes, TWO2 therapy can be used in the presence of infection. The infection should be concomitantly managed as instructed by the treating prescriber.
Yes, TWO2 therapy can be used in combination with appropriate osteomyelitis treatments as instructed by the treating prescriber .
Any gas permeable as instructed by the treating prescriber.
The therapies are not compatible for use at the same time but may be used sequentially.
TWO2 therapy can be used with Patients who have poor circulation. The compression used in TWO2 therapy is cyclical and is not held constant, so therefore does not reduce distal perfusion.
Gas permeable dressings are compatible with TWO2 therapy and may be left in place.
TWO2 therapy may be used in any healthcare setting, including; hospitals, outpatient, as well as, Skilled Nursing Facilities and nursing homes, etc.
There are no known side-effects.
HBOT is the systemic delivery of oxygen though the body by blood vessels that need to be intact for oxygen to reach and help close to the wound. TWO2 therapy is a multimodality that delivers oxygen directly to the wound site and does not rely on good blood circulation. TWO2 therapy provides a higher pressure topical oxygen delivery (pO2 ≈ 800 mmHg) which results in superior tissue oxygenation. This effective delivery of oxygen is combined with cyclical non-contact compression and humidification. TWO2 therapy is convenient for use in settings easily accessible for the patient, is less expensive, and does not have the practical limitations and a number of relative contraindications associated with HBOT.
Over 20,000 patients have been treated with TWO2 therapy. Two million TWO2 treatments have been applied by the patients at home.
What clinical evidence do you have to support the use of TWO2 therapy? Has TWO2 therapy been tested on humans?
TWO2 therapy is supported by a large number of studies. Research results from studies in humans have been published in leading Scientific journals, such as Diabetes Care, Advances in Wound Care, Ostomy and Wound Management (OWM), Vascular and Endovascular Surgery, and International Wound Journal.